Executive Summary The paper aims to discuss the opportunities and challenges of the telemedicine and healthcare information system (HIS) due to its increasing demand and potential advantages to healthcare systems. Many countries, specifically, the US government is very much supportive towards the implementation of integrated HIS and telemedicine technologies in all types of healthcare organizations including hospitals, teaching centres, nursing homes, and individual clinics and physician offices. However, the paper explores that instead of focusing on the implementation of this system, it is important to first address the potential challenges and weaknesses of HIS and telemedicine to improve its performance and efficiency. The research identified that there is a need of system redesign because the current design of this technology is complicated for the end user that encouraged the users to abandon this system and to opt for the traditional methods, which is a waste of financial and human resources. The
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