Chapter 07: Methods of Calculation for Individualized Drug Dosing Kee: Clinical Calculations, 8th Edition OTHER Body Surface Area by Square Root 1. Order: cyclophosphamide 500 mg/m2 in 500 mL of normal saline solution (NSS) over 90 minutes Patient height and weight: 5 ft 10 in, 142 lb Drug available: cyclophosphamide 100 mg dilute with 5 mL of sterile water; yields 20 mg/mL a. What is the patient’s body surface area (BSA) (m2)? b. What is the total dose? c. How many milliliters should you prepare? ANS: a. b. 500 mg/m2 1.78 m2 = 890 mg c. FE: 890 mg/100 mg 5 mL = 44.5 mL OR NURSINGTB.COM 2. Order: cisplatin 50 mg/m2 in 500 mL of NSS intravenously over 90 minutes Patient height and weight: 5 ft 6 in, 160 lb Drug available: cisplatin 100 mg/100 mL a. What is the patient’s BSA (m2)? b. What is the total dose? c. How many milliliters should you prepare? ANS: a. b. 50 mg 1.84 m2 = 92 mg c. FE: 92 mg/100 mg 100 mL = 92 mL OR
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